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1csg

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{{Seed}}
 
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[[Image:1csg.png|left|200px]]
 
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==Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor==
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The line below this paragraph, containing "STRUCTURE_1csg", creates the "Structure Box" on the page.
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<StructureSection load='1csg' size='340' side='right'caption='[[1csg]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1csg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CSG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1csg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1csg OCA], [https://pdbe.org/1csg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1csg RCSB], [https://www.ebi.ac.uk/pdbsum/1csg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1csg ProSAT]</span></td></tr>
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{{STRUCTURE_1csg| PDB=1csg | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSF2_HUMAN CSF2_HUMAN] Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/1csg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1csg ConSurf].
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<div style="clear:both"></div>
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===THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR===
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==See Also==
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*[[Colony-stimulating factor 3D structures|Colony-stimulating factor 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_1569568}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 1569568 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1569568}}
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==About this Structure==
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1CSG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSG OCA].
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==Reference==
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Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor., Walter MR, Cook WJ, Ealick SE, Nagabhushan TL, Trotta PP, Bugg CE, J Mol Biol. 1992 Apr 20;224(4):1075-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1569568 1569568]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Cook, W J.]]
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[[Category: Cook WJ]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick SE]]
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[[Category: Walter, M R.]]
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[[Category: Walter MR]]
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[[Category: Cytokine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:16:57 2008''
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Current revision

Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor

PDB ID 1csg

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