1czd

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{{Seed}}
 
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[[Image:1czd.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4==
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The line below this paragraph, containing "STRUCTURE_1czd", creates the "Structure Box" on the page.
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<StructureSection load='1czd' size='340' side='right'caption='[[1czd]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1czd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CZD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1czd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1czd OCA], [https://pdbe.org/1czd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1czd RCSB], [https://www.ebi.ac.uk/pdbsum/1czd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1czd ProSAT]</span></td></tr>
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{{STRUCTURE_1czd| PDB=1czd | SCENE= }}
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</table>
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== Function ==
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===CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4===
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[https://www.uniprot.org/uniprot/CLAMP_BPT4 CLAMP_BPT4] Sliding clamp that encircles the genomic DNA and links the DNA polymerase to the template to control the processivity of DNA synthesis. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication (PubMed:10535942). Interaction with the sliding-clamp-loader opens the sliding clamp so that it can be loaded around the DNA template (PubMed:22194570). During transcription, encircles the DNA and tethers host RNA polymerase (RNAP) to it (PubMed:33602900).[HAMAP-Rule:MF_04161]<ref>PMID:10535942</ref> <ref>PMID:22194570</ref> <ref>PMID:33602900</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 10698628 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/1czd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_10698628}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1czd ConSurf].
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1CZD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZD OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage., Moarefi I, Jeruzalmi D, Turner J, O'Donnell M, Kuriyan J, J Mol Biol. 2000 Mar 10;296(5):1215-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10698628 10698628]
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__TOC__
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[[Category: Enterobacteria phage t4]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Escherichia virus T4]]
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[[Category: Donnell, M O.]]
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[[Category: Large Structures]]
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[[Category: Jeruzalmi, D.]]
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[[Category: Jeruzalmi D]]
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[[Category: Kuriyan, J.]]
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[[Category: Kuriyan J]]
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[[Category: Moarefi, I.]]
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[[Category: Moarefi I]]
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[[Category: Turner, J.]]
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[[Category: O'Donnell M]]
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[[Category: Bacteriophage t4]]
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[[Category: Turner J]]
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[[Category: Dna replication]]
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[[Category: Processivity clamp]]
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[[Category: Ring-shaped protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:51:40 2008''
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Current revision

CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4

PDB ID 1czd

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