1d2z

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{{Seed}}
 
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[[Image:1d2z.png|left|200px]]
 
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==THREE-DIMENSIONAL STRUCTURE OF A COMPLEX BETWEEN THE DEATH DOMAINS OF PELLE AND TUBE==
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The line below this paragraph, containing "STRUCTURE_1d2z", creates the "Structure Box" on the page.
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<StructureSection load='1d2z' size='340' side='right'caption='[[1d2z]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1d2z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D2Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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{{STRUCTURE_1d2z| PDB=1d2z | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d2z OCA], [https://pdbe.org/1d2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d2z RCSB], [https://www.ebi.ac.uk/pdbsum/1d2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d2z ProSAT]</span></td></tr>
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</table>
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===THREE-DIMENSIONAL STRUCTURE OF A COMPLEX BETWEEN THE DEATH DOMAINS OF PELLE AND TUBE===
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== Function ==
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[https://www.uniprot.org/uniprot/KPEL_DROME KPEL_DROME] Plays an essential role in the Tl receptor signaling pathway that establishes embryonic dorsoventral polarity; the signal directs import of dl into ventral and ventrolateral nuclei, thereby establishing dorsoventral polarity. Tub recruits pll to the plasma membrane and protein-protein interaction activates pll.<ref>PMID:8440018</ref> <ref>PMID:7527496</ref> <ref>PMID:7635064</ref> <ref>PMID:10330490</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10589682 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/1d2z_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10589682}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1D2Z is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D2Z OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d2z ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Three-dimensional structure of a complex between the death domains of Pelle and Tube., Xiao T, Towb P, Wasserman SA, Sprang SR, Cell. 1999 Nov 24;99(5):545-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10589682 10589682]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Sprang, S R.]]
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[[Category: Sprang SR]]
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[[Category: Towb, P.]]
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[[Category: Towb P]]
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[[Category: Wasserman, S A.]]
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[[Category: Wasserman SA]]
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[[Category: Xiao, T.]]
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[[Category: Xiao T]]
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[[Category: Apoptosis]]
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[[Category: Linear array of death domain]]
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[[Category: Plastic interface]]
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[[Category: Six-helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:14:55 2008''
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Current revision

THREE-DIMENSIONAL STRUCTURE OF A COMPLEX BETWEEN THE DEATH DOMAINS OF PELLE AND TUBE

PDB ID 1d2z

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