1d6f

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{{Seed}}
 
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[[Image:1d6f.png|left|200px]]
 
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==CHALCONE SYNTHASE C164A MUTANT==
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The line below this paragraph, containing "STRUCTURE_1d6f", creates the "Structure Box" on the page.
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<StructureSection load='1d6f' size='340' side='right'caption='[[1d6f]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1d6f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D6F FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1d6f| PDB=1d6f | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d6f OCA], [https://pdbe.org/1d6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d6f RCSB], [https://www.ebi.ac.uk/pdbsum/1d6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d6f ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHS2_MEDSA CHS2_MEDSA] The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.<ref>PMID:10653632</ref> <ref>PMID:11732902</ref> <ref>PMID:11959984</ref> <ref>PMID:15380179</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/1d6f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d6f ConSurf].
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<div style="clear:both"></div>
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===CHALCONE SYNTHASE C164A MUTANT===
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==See Also==
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*[[Chalcone synthase|Chalcone synthase]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10653632}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10653632 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_10653632}}
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==About this Structure==
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1D6F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D6F OCA].
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==Reference==
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Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase., Jez JM, Ferrer JL, Bowman ME, Dixon RA, Noel JP, Biochemistry. 2000 Feb 8;39(5):890-902. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10653632 10653632]
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[[Category: Medicago sativa]]
[[Category: Medicago sativa]]
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[[Category: Naringenin-chalcone synthase]]
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[[Category: Bowman ME]]
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[[Category: Single protein]]
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[[Category: Dixon RA]]
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[[Category: Bowman, M E.]]
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[[Category: Ferrer JL]]
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[[Category: Dixon, R A.]]
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[[Category: Jez JM]]
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[[Category: Ferrer, J L.]]
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[[Category: Noel JP]]
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[[Category: Jez, J M.]]
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[[Category: Noel, J P.]]
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[[Category: Flavonoid biosynthesis]]
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[[Category: Malonyl-coa decarboxylation]]
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[[Category: Polypetide synthase]]
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[[Category: Site- directed mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:32:03 2008''
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Current revision

CHALCONE SYNTHASE C164A MUTANT

PDB ID 1d6f

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