1d8l

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{{Seed}}
 
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[[Image:1d8l.png|left|200px]]
 
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==E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III==
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The line below this paragraph, containing "STRUCTURE_1d8l", creates the "Structure Box" on the page.
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<StructureSection load='1d8l' size='340' side='right'caption='[[1d8l]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1d8l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D8L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d8l OCA], [https://pdbe.org/1d8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d8l RCSB], [https://www.ebi.ac.uk/pdbsum/1d8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d8l ProSAT]</span></td></tr>
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{{STRUCTURE_1d8l| PDB=1d8l | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RUVA_ECOLI RUVA_ECOLI] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.<ref>PMID:8433990</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/1d8l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d8l ConSurf].
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<div style="clear:both"></div>
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===E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III===
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10772859 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_10772859}}
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==About this Structure==
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1D8L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D8L OCA].
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==Reference==
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Modulation of RuvB function by the mobile domain III of the Holliday junction recognition protein RuvA., Nishino T, Iwasaki H, Kataoka M, Ariyoshi M, Fujita T, Shinagawa H, Morikawa K, J Mol Biol. 2000 May 5;298(3):407-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10772859 10772859]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ariyoshi, M.]]
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[[Category: Ariyoshi M]]
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[[Category: Fujita, T.]]
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[[Category: Fujita T]]
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[[Category: Iwasaki, H.]]
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[[Category: Iwasaki H]]
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[[Category: Kataoka, M.]]
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[[Category: Kataoka M]]
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[[Category: Morikawa, K.]]
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[[Category: Morikawa K]]
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[[Category: Nishino, T.]]
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[[Category: Nishino T]]
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[[Category: Shinagawa, H.]]
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[[Category: Shinagawa H]]
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[[Category: Gene regulation]]
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[[Category: Helix-hairpin-helix motif]]
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[[Category: Ob-fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:40:41 2008''
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Current revision

E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III

PDB ID 1d8l

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