1di0

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{{Seed}}
 
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[[Image:1di0.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF LUMAZINE SYNTHASE FROM BRUCELLA ABORTUS==
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The line below this paragraph, containing "STRUCTURE_1di0", creates the "Structure Box" on the page.
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<StructureSection load='1di0' size='340' side='right'caption='[[1di0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1di0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_abortus Brucella abortus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DI0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1di0| PDB=1di0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1di0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1di0 OCA], [https://pdbe.org/1di0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1di0 RCSB], [https://www.ebi.ac.uk/pdbsum/1di0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1di0 ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF LUMAZINE SYNTHASE FROM BRUCELLA ABORTUS===
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== Function ==
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[https://www.uniprot.org/uniprot/RISB2_BRUAB RISB2_BRUAB] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. Displays low catalytic activity in comparison with the isozyme RibH1.<ref>PMID:10482294</ref> <ref>PMID:16165152</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10764570 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/di/1di0_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10764570}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1DI0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Brucella_abortus Brucella abortus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DI0 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1di0 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus., Braden BC, Velikovsky CA, Cauerhff AA, Polikarpov I, Goldbaum FA, J Mol Biol. 2000 Apr 14;297(5):1031-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10764570 10764570]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Brucella abortus]]
[[Category: Brucella abortus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Braden, B C.]]
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[[Category: Braden BC]]
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[[Category: Cauerhff, A A.]]
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[[Category: Cauerhff AA]]
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[[Category: Goldbaum, F A.]]
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[[Category: Goldbaum FA]]
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[[Category: Polikarpov, I.]]
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[[Category: Polikarpov I]]
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[[Category: Velikovsky, C A.]]
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[[Category: Velikovsky CA]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:05:21 2008''
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Current revision

CRYSTAL STRUCTURE OF LUMAZINE SYNTHASE FROM BRUCELLA ABORTUS

PDB ID 1di0

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