1dkh

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{{Seed}}
 
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[[Image:1dkh.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE HEMOPHORE HASA, PH 6.5==
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The line below this paragraph, containing "STRUCTURE_1dkh", creates the "Structure Box" on the page.
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<StructureSection load='1dkh' size='340' side='right'caption='[[1dkh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1dkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DKH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1dkh| PDB=1dkh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dkh OCA], [https://pdbe.org/1dkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dkh RCSB], [https://www.ebi.ac.uk/pdbsum/1dkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dkh ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF THE HEMOPHORE HASA, PH 6.5===
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== Function ==
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[https://www.uniprot.org/uniprot/HASA_SERMA HASA_SERMA] Can bind free heme and also acquire it from hemoglobin. Conveys heme from hemoglobin to the HasR receptor which releases it into the bacterium. HasR alone can take up heme but the synergy between HasA and HasR increases heme uptake 100-fold.<ref>PMID:7937909</ref> <ref>PMID:9171402</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10966573 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/1dkh_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10966573}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1DKH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKH OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dkh ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms., Arnoux P, Haser R, Izadi-Pruneyre N, Lecroisey A, Czjzek M, Proteins. 2000 Nov 1;41(2):202-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10966573 10966573]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Serratia marcescens]]
[[Category: Serratia marcescens]]
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[[Category: Single protein]]
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[[Category: Arnoux P]]
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[[Category: Arnoux, P.]]
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[[Category: Czjzek M]]
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[[Category: Czjzek, M.]]
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[[Category: Haser R]]
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[[Category: Haser, R.]]
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[[Category: Izadi-Pruneyre N]]
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[[Category: Izadi-Pruneyre, N.]]
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[[Category: Lecroisey A]]
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[[Category: Lecroisey, A.]]
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[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:12:22 2008''
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Current revision

CRYSTAL STRUCTURE OF THE HEMOPHORE HASA, PH 6.5

PDB ID 1dkh

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