1dof

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{{Seed}}
 
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[[Image:1dof.png|left|200px]]
 
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==THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY==
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The line below this paragraph, containing "STRUCTURE_1dof", creates the "Structure Box" on the page.
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<StructureSection load='1dof' size='340' side='right'caption='[[1dof]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1dof]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DOF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dof OCA], [https://pdbe.org/1dof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dof RCSB], [https://www.ebi.ac.uk/pdbsum/1dof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dof ProSAT]</span></td></tr>
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{{STRUCTURE_1dof| PDB=1dof | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8ZY28_PYRAE Q8ZY28_PYRAE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/1dof_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dof ConSurf].
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<div style="clear:both"></div>
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===THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY===
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==See Also==
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*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10926519}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10926519 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10926519}}
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==About this Structure==
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1DOF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DOF OCA].
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==Reference==
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The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds., Toth EA, Worby C, Dixon JE, Goedken ER, Marqusee S, Yeates TO, J Mol Biol. 2000 Aug 11;301(2):433-50. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10926519 10926519]
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[[Category: Adenylosuccinate lyase]]
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[[Category: Pyrobaculum aerophilum]]
[[Category: Pyrobaculum aerophilum]]
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[[Category: Single protein]]
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[[Category: Dixon JE]]
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[[Category: Dixon, J E.]]
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[[Category: Goedken E]]
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[[Category: Goedken, E.]]
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[[Category: Marqusee S]]
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[[Category: Marqusee, S.]]
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[[Category: Toth EA]]
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[[Category: Toth, E A.]]
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[[Category: Yeates TO]]
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[[Category: Yeates, T O.]]
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[[Category: Lyase]]
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[[Category: Purine biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:22:39 2008''
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Current revision

THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY

PDB ID 1dof

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