1dtp

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{{Seed}}
 
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[[Image:1dtp.png|left|200px]]
 
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==THE STRUCTURE OF THE ISOLATED CATALYTIC DOMAIN OF DIPHTHERIA TOXIN==
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The line below this paragraph, containing "STRUCTURE_1dtp", creates the "Structure Box" on the page.
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<StructureSection load='1dtp' size='340' side='right'caption='[[1dtp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1dtp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynephage_beta Corynephage beta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APU:ADENYLYL-3-5-PHOSPHO-URIDINE-3-MONOPHOSPHATE'>APU</scene></td></tr>
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{{STRUCTURE_1dtp| PDB=1dtp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dtp OCA], [https://pdbe.org/1dtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dtp RCSB], [https://www.ebi.ac.uk/pdbsum/1dtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dtp ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DTX_CORBE DTX_CORBE] Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.<ref>PMID:18276581</ref> <ref>PMID:19793133</ref>
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===THE STRUCTURE OF THE ISOLATED CATALYTIC DOMAIN OF DIPHTHERIA TOXIN===
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==See Also==
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*[[Diphtheria toxin|Diphtheria toxin]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 7827036 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_7827036}}
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==About this Structure==
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1DTP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Corynephage_beta Corynephage beta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTP OCA].
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==Reference==
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Structure of the isolated catalytic domain of diphtheria toxin., Weiss MS, Blanke SR, Collier RJ, Eisenberg D, Biochemistry. 1995 Jan 24;34(3):773-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7827036 7827036]
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[[Category: Corynephage beta]]
[[Category: Corynephage beta]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Eisenberg, D.]]
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[[Category: Eisenberg D]]
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[[Category: Weiss, M S.]]
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[[Category: Weiss MS]]
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[[Category: Toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:36:09 2008''
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Current revision

THE STRUCTURE OF THE ISOLATED CATALYTIC DOMAIN OF DIPHTHERIA TOXIN

PDB ID 1dtp

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