This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1e3u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:58, 20 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1e3u.png|left|200px]]
 
-
<!--
+
==MAD structure of OXA10 class D beta-lactamase==
-
The line below this paragraph, containing "STRUCTURE_1e3u", creates the "Structure Box" on the page.
+
<StructureSection load='1e3u' size='340' side='right'caption='[[1e3u]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1e3u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E3U FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AUC:GOLD+(I)+CYANIDE+ION'>AUC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_1e3u| PDB=1e3u | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e3u OCA], [https://pdbe.org/1e3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e3u RCSB], [https://www.ebi.ac.uk/pdbsum/1e3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e3u ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLO10_PSEAI BLO10_PSEAI] Hydrolyzes both carbenicillin and oxacillin.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/1e3u_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e3u ConSurf].
 +
<div style="clear:both"></div>
-
===MAD STRUCTURE OF OXA10 CLASS D BETA-LACTAMASE===
+
==See Also==
-
 
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11188693}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 11188693 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_11188693}}
+
-
 
+
-
==About this Structure==
+
-
1E3U is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3U OCA].
+
-
 
+
-
==Reference==
+
-
Insights into class D beta-lactamases are revealed by the crystal structure of the OXA10 enzyme from Pseudomonas aeruginosa., Maveyraud L, Golemi D, Kotra LP, Tranier S, Vakulenko S, Mobashery S, Samama JP, Structure. 2000 Dec 15;8(12):1289-98. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11188693 11188693]
+
-
[[Category: Beta-lactamase]]
+
-
[[Category: Protein complex]]
+
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
-
[[Category: Golemi, D.]]
+
[[Category: Golemi D]]
-
[[Category: Kotra, L P.]]
+
[[Category: Kotra LP]]
-
[[Category: Maveyraud, L.]]
+
[[Category: Maveyraud L]]
-
[[Category: Mobashery, S.]]
+
[[Category: Mobashery S]]
-
[[Category: Samama, J P.]]
+
[[Category: Samama JP]]
-
[[Category: Tranier, S.]]
+
[[Category: Tranier S]]
-
[[Category: Vakulenko, S.]]
+
[[Category: Vakulenko S]]
-
[[Category: Antiobitic resistance]]
+
-
[[Category: Beta-lactamase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:06:24 2008''
+

Current revision

MAD structure of OXA10 class D beta-lactamase

PDB ID 1e3u

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1e3u"
Personal tools