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1ebd

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{{Seed}}
 
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[[Image:1ebd.png|left|200px]]
 
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==DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING DOMAIN OF THE DIHYDROLIPOAMIDE ACETYLASE==
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The line below this paragraph, containing "STRUCTURE_1ebd", creates the "Structure Box" on the page.
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<StructureSection load='1ebd' size='340' side='right'caption='[[1ebd]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ebd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. The September 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Pyruvate Dehydrogenase Complex'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_9 10.2210/rcsb_pdb/mom_2012_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EBD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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{{STRUCTURE_1ebd| PDB=1ebd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ebd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ebd OCA], [https://pdbe.org/1ebd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ebd RCSB], [https://www.ebi.ac.uk/pdbsum/1ebd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ebd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DLDH1_GEOSE DLDH1_GEOSE] Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/1ebd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ebd ConSurf].
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<div style="clear:both"></div>
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===DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING DOMAIN OF THE DIHYDROLIPOAMIDE ACETYLASE===
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==See Also==
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*[[Dihydrolipoamide acetyltransferase 3D structures|Dihydrolipoamide acetyltransferase 3D structures]]
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*[[Dihydrolipoamide dehydrogenase|Dihydrolipoamide dehydrogenase]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 8805537 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8805537}}
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==About this Structure==
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1EBD is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EBD OCA].
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==Reference==
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Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase., Mande SS, Sarfaty S, Allen MD, Perham RN, Hol WG, Structure. 1996 Mar 15;4(3):277-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8805537 8805537]
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[[Category: Dihydrolipoyl dehydrogenase]]
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[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Allen, M D.]]
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[[Category: Pyruvate Dehydrogenase Complex]]
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[[Category: Hol, W G.J.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Mande, S S.]]
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[[Category: Allen MD]]
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[[Category: Perham, R N.]]
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[[Category: Hol WGJ]]
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[[Category: Sarfaty, S.]]
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[[Category: Mande SS]]
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[[Category: Glycolysis]]
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[[Category: Perham RN]]
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[[Category: Oxidoreductase]]
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[[Category: Sarfaty S]]
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[[Category: Redox-active center]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:26:58 2008''
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Current revision

DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING DOMAIN OF THE DIHYDROLIPOAMIDE ACETYLASE

PDB ID 1ebd

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