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1egp

From Proteopedia

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{{Seed}}
 
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[[Image:1egp.png|left|200px]]
 
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==PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER==
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The line below this paragraph, containing "STRUCTURE_1egp", creates the "Structure Box" on the page.
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<StructureSection load='1egp' size='340' side='right'caption='[[1egp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1egp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EGP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1egp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1egp OCA], [https://pdbe.org/1egp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1egp RCSB], [https://www.ebi.ac.uk/pdbsum/1egp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1egp ProSAT]</span></td></tr>
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{{STRUCTURE_1egp| PDB=1egp | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ICIC_HIRME ICIC_HIRME] Inhibits both elastase and cathepsin G.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/1egp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1egp ConSurf].
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<div style="clear:both"></div>
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===PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER===
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==See Also==
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*[[Eglin|Eglin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8425603}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8425603 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8425603}}
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==About this Structure==
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1EGP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGP OCA].
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==Reference==
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Structure of the proteinase inhibitor eglin c with hydrolysed reactive centre at 2.0 A resolution., Betzel C, Dauter Z, Genov N, Lamzin V, Navaza J, Schnebli HP, Visanji M, Wilson KS, FEBS Lett. 1993 Feb 15;317(3):185-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8425603 8425603]
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[[Category: Hirudo medicinalis]]
[[Category: Hirudo medicinalis]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Betzel, C.]]
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[[Category: Betzel C]]
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[[Category: Dauter, Z.]]
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[[Category: Dauter Z]]
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[[Category: Lamzin, V.]]
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[[Category: Lamzin V]]
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[[Category: Wilson, K S.]]
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[[Category: Wilson KS]]
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[[Category: Proteinase inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:40:20 2008''
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Current revision

PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER

PDB ID 1egp

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