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1ei1

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{{Seed}}
 
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[[Image:1ei1.png|left|200px]]
 
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==DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER==
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The line below this paragraph, containing "STRUCTURE_1ei1", creates the "Structure Box" on the page.
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<StructureSection load='1ei1' size='340' side='right'caption='[[1ei1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ei1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EI1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EI1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1ei1| PDB=1ei1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ei1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ei1 OCA], [https://pdbe.org/1ei1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ei1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ei1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ei1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/1ei1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ei1 ConSurf].
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<div style="clear:both"></div>
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===DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER===
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==See Also==
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*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10734094 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_10734094}}
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==About this Structure==
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1EI1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EI1 OCA].
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==Reference==
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Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center., Brino L, Urzhumtsev A, Mousli M, Bronner C, Mitschler A, Oudet P, Moras D, J Biol Chem. 2000 Mar 31;275(13):9468-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10734094 10734094]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Brino, L.]]
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[[Category: Brino L]]
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[[Category: Moras, D.]]
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[[Category: Moras D]]
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[[Category: Oudet, P.]]
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[[Category: Oudet P]]
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[[Category: Urzhumtsev, A.]]
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[[Category: Urzhumtsev A]]
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[[Category: Al, et]]
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[[Category: Atpase domain]]
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[[Category: Dimer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:43:31 2008''
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Current revision

DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER

PDB ID 1ei1

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