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1ei9

From Proteopedia

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{{Seed}}
 
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[[Image:1ei9.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1==
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The line below this paragraph, containing "STRUCTURE_1ei9", creates the "Structure Box" on the page.
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<StructureSection load='1ei9' size='340' side='right'caption='[[1ei9]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ei9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EI9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1ei9| PDB=1ei9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ei9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ei9 OCA], [https://pdbe.org/1ei9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ei9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ei9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ei9 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PPT1_BOVIN PPT1_BOVIN] Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/1ei9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ei9 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1===
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==See Also==
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*[[Thioesterase 3D structures|Thioesterase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10781062}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10781062 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10781062}}
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==About this Structure==
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1EI9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EI9 OCA].
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==Reference==
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The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis., Bellizzi JJ 3rd, Widom J, Kemp C, Lu JY, Das AK, Hofmann SL, Clardy J, Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4573-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10781062 10781062]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Palmitoyl-protein hydrolase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Bellizzi III JJ]]
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[[Category: Clardy, J.]]
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[[Category: Clardy J]]
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[[Category: Das, A K.]]
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[[Category: Das AK]]
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[[Category: Hofmann, S L.]]
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[[Category: Hofmann SL]]
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[[Category: III, J J.Bellizzi.]]
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[[Category: Kemp C]]
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[[Category: Kemp, C.]]
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[[Category: Lu JY]]
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[[Category: Lu, J Y.]]
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[[Category: Widom J]]
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[[Category: Widom, J.]]
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[[Category: Alpha/beta hydrolase]]
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[[Category: Glycoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:44:30 2008''
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Current revision

CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1

PDB ID 1ei9

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