1ej8

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[[Image:1ej8.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_1ej8", creates the "Structure Box" on the page.
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<StructureSection load='1ej8' size='340' side='right'caption='[[1ej8]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ej8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJ8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1ej8| PDB=1ej8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ej8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ej8 OCA], [https://pdbe.org/1ej8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ej8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ej8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ej8 ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION===
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== Function ==
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[https://www.uniprot.org/uniprot/CCS1_YEAST CCS1_YEAST] Copper chaperone for apo superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to apo-SOD1.<ref>PMID:9295278</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10736160 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/1ej8_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10736160}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1EJ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ8 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ej8 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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X-ray crystallographic and analytical ultracentrifugation analyses of truncated and full-length yeast copper chaperones for SOD (LYS7): a dimer-dimer model of LYS7-SOD association and copper delivery., Hall LT, Sanchez RJ, Holloway SP, Zhu H, Stine JE, Lyons TJ, Demeler B, Schirf V, Hansen JC, Nersissian AM, Valentine JS, Hart PJ, Biochemistry. 2000 Apr 4;39(13):3611-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10736160 10736160]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Demeler B]]
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[[Category: Demeler, B.]]
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[[Category: Hall LT]]
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[[Category: Hall, L T.]]
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[[Category: Hansen JC]]
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[[Category: Hansen, J C.]]
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[[Category: Hart PJ]]
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[[Category: Hart, P J.]]
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[[Category: Holloway SP]]
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[[Category: Holloway, S P.]]
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[[Category: Lyons TJ]]
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[[Category: Lyons, T J.]]
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[[Category: Nersissian AM]]
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[[Category: Nersissian, A M.]]
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[[Category: Sanchez RJ]]
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[[Category: Sanchez, R J.]]
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[[Category: Schirf V]]
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[[Category: Schirf, V.]]
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[[Category: Stine JE]]
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[[Category: Stine, J E.]]
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[[Category: Valentine JS]]
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[[Category: Valentine, J S.]]
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[[Category: Zhu H]]
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[[Category: Zhu, H.]]
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[[Category: Beta barrel]]
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[[Category: Copper chaperone for sod]]
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[[Category: Domain 2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:49:57 2008''
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Current revision

CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION

PDB ID 1ej8

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