This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ejb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:03, 7 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1ejb.png|left|200px]]
 
-
<!--
+
==LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE==
-
The line below this paragraph, containing "STRUCTURE_1ejb", creates the "Structure Box" on the page.
+
<StructureSection load='1ejb' size='340' side='right'caption='[[1ejb]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ejb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJB FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=INJ:5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC+ACID'>INJ</scene></td></tr>
-
{{STRUCTURE_1ejb| PDB=1ejb | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ejb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ejb OCA], [https://pdbe.org/1ejb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ejb RCSB], [https://www.ebi.ac.uk/pdbsum/1ejb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ejb ProSAT]</span></td></tr>
-
 
+
</table>
-
===LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/RIB4_YEAST RIB4_YEAST] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<ref>PMID:7559556</ref> <ref>PMID:8969176</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_10860731}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 10860731 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/1ejb_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_10860731}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1EJB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJB OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ejb ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue., Meining W, Mortl S, Fischer M, Cushman M, Bacher A, Ladenstein R, J Mol Biol. 2000 May 26;299(1):181-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10860731 10860731]
+
<references/>
-
[[Category: Riboflavin synthase]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Single protein]]
+
[[Category: Bacher A]]
-
[[Category: Bacher, A.]]
+
[[Category: Cushman M]]
-
[[Category: Cushman, M.]]
+
[[Category: Fischer M]]
-
[[Category: Fischer, M.]]
+
[[Category: Ladenstein R]]
-
[[Category: Ladenstein, R.]]
+
[[Category: Meining W]]
-
[[Category: Meining, W.]]
+
[[Category: Mortl S]]
-
[[Category: Mortl, S.]]
+
-
[[Category: Inhibitor complex]]
+
-
[[Category: Lumazine synthase]]
+
-
[[Category: Saccharomyces cerevisiae]]
+
-
[[Category: Vitamin biosynthesis]]
+
-
[[Category: X-ray structure analysis]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:50:19 2008''
+

Current revision

LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE

PDB ID 1ejb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ejb"
Personal tools