1ep0

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{{Seed}}
 
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[[Image:1ep0.png|left|200px]]
 
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==HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM==
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The line below this paragraph, containing "STRUCTURE_1ep0", creates the "Structure Box" on the page.
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<StructureSection load='1ep0' size='340' side='right'caption='[[1ep0]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ep0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EP0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ep0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ep0 OCA], [https://pdbe.org/1ep0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ep0 RCSB], [https://www.ebi.ac.uk/pdbsum/1ep0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ep0 ProSAT], [https://www.topsan.org/Proteins/NESGC/1ep0 TOPSAN]</span></td></tr>
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{{STRUCTURE_1ep0| PDB=1ep0 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RMLC_METTH RMLC_METTH] Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.<ref>PMID:10827167</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/1ep0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ep0 ConSurf].
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<div style="clear:both"></div>
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===HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM===
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==See Also==
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*[[RmlC|RmlC]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10827167}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10827167 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_10827167}}
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==About this Structure==
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1EP0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EP0 OCA].
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==Reference==
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Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP., Christendat D, Saridakis V, Dharamsi A, Bochkarev A, Pai EF, Arrowsmith CH, Edwards AM, J Biol Chem. 2000 Aug 11;275(32):24608-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10827167 10827167]
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[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: DTDP-4-dehydrorhamnose 3,5-epimerase]]
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[[Category: Bochkarev A]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Christendat D]]
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[[Category: Bochkarev, A.]]
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[[Category: Edwards AM]]
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[[Category: Christendat, D.]]
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[[Category: Pai EF]]
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[[Category: Edwards, A M.]]
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[[Category: Saridakis V]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Pai, E F.]]
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[[Category: Saridakis, V.]]
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[[Category: Dtdp-4-dehydrorhamnose epimerase]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Racemase]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:24:41 2008''
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Current revision

HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM

PDB ID 1ep0

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