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1epo

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ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)

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Retrieved from "http://52.214.119.220/wiki/index.php/1epo"

Categories: Cryphonectria parasitica | Large Structures | Blundell TL | Cooper JB | Veerapandian B

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:1epo.png|left|200px]]
-<!--
+==ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)==
-The line below this paragraph, containing "STRUCTURE_1epo", creates the "Structure Box" on the page.
+<StructureSection load='1epo' size='340' side='right'caption='[[1epo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1epo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EPO FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2Z3:N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANYL-N-[(1R)-1-(CYCLOHEXYLMETHYL)-3,3-DIFLUORO-2,2-DIHYDROXY-4-(METHYLAMINO)-4-OXOBUTYL]-L-NORLEUCINAMIDE'>2Z3</scene></td></tr>
-{{STRUCTURE_1epo|  PDB=1epo  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1epo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1epo OCA], [https://pdbe.org/1epo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1epo RCSB], [https://www.ebi.ac.uk/pdbsum/1epo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1epo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/1epo_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1epo ConSurf].
+<div style="clear:both"></div>
-===DIRECT OBSERVATION BY X-RAY ANALYSIS OF THE TETRAHEDRAL "INTERMEDIATE" OF ASPARTIC PROTEINASES===
+==See Also==
+*[[Pepsin|Pepsin]]
+*[[Proteinase 3D structures|Proteinase 3D structures]]
-<!--
+__TOC__
-The line below this paragraph, {{ABSTRACT_PUBMED_1304340}}, adds the Publication Abstract to the page
+</StructureSection>
-(as it appears on PubMed at http://www.pubmed.gov), where 1304340 is the PubMed ID number.
+[[Category: Cryphonectria parasitica]]
--->
+[[Category: Large Structures]]
-{{ABSTRACT_PUBMED_1304340}}
+[[Category: Blundell TL]]
+[[Category: Cooper JB]]
-==About this Structure==
+[[Category: Veerapandian B]]
-EPO is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EPO OCA].
-==Reference==
-Direct observation by X-ray analysis of the tetrahedral "intermediate" of aspartic proteinases., Veerapandian B, Cooper JB, Sali A, Blundell TL, Rosati RL, Dominy BW, Damon DB, Hoover DJ, Protein Sci. 1992 Mar;1(3):322-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1304340 1304340]
-[[Category: Endothiapepsin]]
-[[Category: Single protein]]
-[[Category: Blundell, T L.]]
-[[Category: Cooper, J B.]]
-[[Category: Veerapandian, B.]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:32:30 2008''

1epo

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Current revision

ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)

Structural highlights

Function

Evolutionary Conservation

See Also

Contents

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