1erz

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{{Seed}}
 
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[[Image:1erz.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES==
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The line below this paragraph, containing "STRUCTURE_1erz", creates the "Structure Box" on the page.
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<StructureSection load='1erz' size='340' side='right'caption='[[1erz]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1erz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_sp._KNK712 Agrobacterium sp. KNK712]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ERZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ERZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1erz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1erz OCA], [https://pdbe.org/1erz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1erz RCSB], [https://www.ebi.ac.uk/pdbsum/1erz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1erz ProSAT]</span></td></tr>
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{{STRUCTURE_1erz| PDB=1erz | SCENE= }}
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</table>
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== Function ==
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===CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES===
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[https://www.uniprot.org/uniprot/DCAS_AGRSK DCAS_AGRSK] The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_10903946}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 10903946 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/1erz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_10903946}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1erz ConSurf].
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1ERZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ERZ OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of N-carbamyl-D-amino acid amidohydrolase with a novel catalytic framework common to amidohydrolases., Nakai T, Hasegawa T, Yamashita E, Yamamoto M, Kumasaka T, Ueki T, Nanba H, Ikenaka Y, Takahashi S, Sato M, Tsukihara T, Structure. 2000 Jul 15;8(7):729-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10903946 10903946]
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[[Category: Agrobacterium sp. KNK712]]
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[[Category: Agrobacterium sp.]]
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[[Category: Large Structures]]
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[[Category: N-carbamoyl-D-amino acid hydrolase]]
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[[Category: Hasegawa T]]
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[[Category: Single protein]]
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[[Category: Ikenaka Y]]
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[[Category: Hasegawa, T.]]
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[[Category: Kumasaka T]]
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[[Category: Ikenaka, Y.]]
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[[Category: Nakai T]]
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[[Category: Kumasaka, T.]]
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[[Category: Nanba H]]
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[[Category: Nakai, T.]]
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[[Category: Sato M]]
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[[Category: Nanba, H.]]
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[[Category: Takahashi S]]
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[[Category: Sato, M.]]
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[[Category: Tsukihara T]]
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[[Category: Takahashi, S.]]
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[[Category: Ueki T]]
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[[Category: Tsukihara, T.]]
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[[Category: Yamamoto M]]
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[[Category: Ueki, T.]]
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[[Category: Yamashita E]]
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[[Category: Yamamoto, M.]]
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[[Category: Yamashita, E.]]
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[[Category: Four-layer sandwich]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:47:05 2008''
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Current revision

CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES

PDB ID 1erz

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