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1evw

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{{Seed}}
 
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[[Image:1evw.png|left|200px]]
 
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==L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.==
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The line below this paragraph, containing "STRUCTURE_1evw", creates the "Structure Box" on the page.
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<StructureSection load='1evw' size='340' side='right'caption='[[1evw]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1evw]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Physarum_polycephalum Physarum polycephalum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1evw| PDB=1evw | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evw OCA], [https://pdbe.org/1evw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evw RCSB], [https://www.ebi.ac.uk/pdbsum/1evw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PPO1_PHYPO PPO1_PHYPO] Mediates the homing of a group I intron in the ribosomal DNA. Makes a four-base staggered cut in its ribosomal DNA target sequence.
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===L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.===
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10891275 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10891275}}
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==About this Structure==
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1EVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Physarum_polycephalum Physarum polycephalum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVW OCA].
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==Reference==
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Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site., Galburt EA, Chadsey MS, Jurica MS, Chevalier BS, Erho D, Tang W, Monnat RJ Jr, Stoddard BL, J Mol Biol. 2000 Jul 21;300(4):877-87. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10891275 10891275]
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[[Category: Physarum polycephalum]]
[[Category: Physarum polycephalum]]
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[[Category: Single protein]]
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[[Category: Chevalier BS]]
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[[Category: Chevalier, B S.]]
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[[Category: Erho D]]
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[[Category: Erho, D.]]
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[[Category: Galburt EA]]
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[[Category: Galburt, E A.]]
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[[Category: Jurica MS]]
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[[Category: Jurica, M S.]]
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[[Category: Stoddard BL]]
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[[Category: Stoddard, B L.]]
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[[Category: Bent dna]]
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[[Category: C-terminal exchanged dimer interface]]
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[[Category: Dna binding b-sheet]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:06:10 2008''
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Current revision

L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.

PDB ID 1evw

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