This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ey3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:22, 13 March 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1ey3.png|left|200px]]
 
-
<!--
+
==STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA==
-
The line below this paragraph, containing "STRUCTURE_1ey3", creates the "Structure Box" on the page.
+
<StructureSection load='1ey3' size='340' side='right'caption='[[1ey3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ey3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EY3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAK:4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA'>DAK</scene></td></tr>
-
{{STRUCTURE_1ey3| PDB=1ey3 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ey3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ey3 OCA], [https://pdbe.org/1ey3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ey3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ey3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ey3 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ECHM_RAT ECHM_RAT] Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ey/1ey3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ey3 ConSurf].
 +
<div style="clear:both"></div>
-
===STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA===
+
==See Also==
-
 
+
*[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11851409}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 11851409 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_11851409}}
+
-
 
+
-
==About this Structure==
+
-
1EY3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EY3 OCA].
+
-
 
+
-
==Reference==
+
-
Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion., Bahnson BJ, Anderson VE, Petsko GA, Biochemistry. 2002 Feb 26;41(8):2621-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11851409 11851409]
+
-
[[Category: Enoyl-CoA hydratase]]
+
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
-
[[Category: Single protein]]
+
[[Category: Anderson VE]]
-
[[Category: Anderson, V E.]]
+
[[Category: Bahnson BJ]]
-
[[Category: Bahnson, B J.]]
+
[[Category: Petsko GA]]
-
[[Category: Petsko, G A.]]
+
-
[[Category: Beta-elimination]]
+
-
[[Category: Beta-oxidation]]
+
-
[[Category: Concerted reaction]]
+
-
[[Category: Crotonase]]
+
-
[[Category: Enoyl-coa hydratase]]
+
-
[[Category: Fatty acid metabolism]]
+
-
[[Category: Syn-addition]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:11:47 2008''
+

Current revision

STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA

PDB ID 1ey3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ey3"
Personal tools