This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1f39

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:09, 20 March 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1f39.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN==
-
The line below this paragraph, containing "STRUCTURE_1f39", creates the "Structure Box" on the page.
+
<StructureSection load='1f39' size='340' side='right'caption='[[1f39]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1f39]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F39 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f39 OCA], [https://pdbe.org/1f39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f39 RCSB], [https://www.ebi.ac.uk/pdbsum/1f39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f39 ProSAT]</span></td></tr>
-
{{STRUCTURE_1f39| PDB=1f39 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN===
+
[https://www.uniprot.org/uniprot/RPC1_LAMBD RPC1_LAMBD] Repressor protein CI allows phage lambda to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein CI to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_10892750}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 10892750 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/1f39_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_10892750}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f39 ConSurf].
-
1F39 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F39 OCA].
+
<div style="clear:both"></div>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding., Bell CE, Frescura P, Hochschild A, Lewis M, Cell. 2000 Jun 23;101(7):801-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10892750 10892750]
+
[[Category: Escherichia virus Lambda]]
-
[[Category: Enterobacteria phage lambda]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Bell CE]]
-
[[Category: Bell, C E.]]
+
[[Category: Frescura P]]
-
[[Category: Frescura, P.]]
+
[[Category: Hochschild A]]
-
[[Category: Hochschild, A.]]
+
[[Category: Lewis M]]
-
[[Category: Lewis, M.]]
+
-
[[Category: Cooperative operator binding]]
+
-
[[Category: Gene regulation]]
+
-
[[Category: Reca-mediated self-cleavage]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:35:40 2008''
+

Current revision

CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN

PDB ID 1f39

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1f39"
Personal tools