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1f8n

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{{Seed}}
 
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[[Image:1f8n.png|left|200px]]
 
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==LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT==
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The line below this paragraph, containing "STRUCTURE_1f8n", creates the "Structure Box" on the page.
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<StructureSection load='1f8n' size='340' side='right'caption='[[1f8n]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1f8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F8N FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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{{STRUCTURE_1f8n| PDB=1f8n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f8n OCA], [https://pdbe.org/1f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f8n RCSB], [https://www.ebi.ac.uk/pdbsum/1f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f8n ProSAT]</span></td></tr>
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</table>
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===LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT===
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== Function ==
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[https://www.uniprot.org/uniprot/LOX1_SOYBN LOX1_SOYBN] Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. With linoleate as substrate, L-1 shows a preference for carbon 13 as the site for hydroperoxidation (in contrast to L-2 and L-3, which utilize either carbon 9 or 13). At pH above 8.5, only (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate is produced, but as the pH decreases, the proportion of (9S)-hydroperoxide increases linearly until at pH 6.0 it represents about 25 % of the products.<ref>PMID:16157595</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11412104}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11412104 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/1f8n_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11412104}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1F8N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8N OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f8n ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1., Tomchick DR, Phan P, Cymborowski M, Minor W, Holman TR, Biochemistry. 2001 Jun 26;40(25):7509-17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11412104 11412104]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Glycine max]]
[[Category: Glycine max]]
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[[Category: Lipoxygenase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Holman T]]
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[[Category: Holman, T.]]
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[[Category: Minor W]]
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[[Category: Minor, W.]]
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[[Category: Tomchick DR]]
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[[Category: Tomchick, D R.]]
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[[Category: Dioxygenase]]
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[[Category: Fatty acid]]
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[[Category: Lipoxygenase]]
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[[Category: Metalloprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:52:15 2008''
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Current revision

LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT

PDB ID 1f8n

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