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1f9o

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{{Seed}}
 
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[[Image:1f9o.png|left|200px]]
 
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==Crystal structure of the cellulase Cel48F from C. Cellulolyticum with the thiooligosaccharide inhibitor PIPS-IG3==
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The line below this paragraph, containing "STRUCTURE_1f9o", creates the "Structure Box" on the page.
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<StructureSection load='1f9o' size='340' side='right'caption='[[1f9o]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1f9o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruminiclostridium_cellulolyticum Ruminiclostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F9O FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=V3P:4-iodophenyl+1,4-dithio-beta-D-glucopyranoside'>V3P</scene></td></tr>
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{{STRUCTURE_1f9o| PDB=1f9o | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f9o OCA], [https://pdbe.org/1f9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f9o RCSB], [https://www.ebi.ac.uk/pdbsum/1f9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f9o ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUNF_RUMCH GUNF_RUMCH] Probable endoglucanase involved in the degradation of cellulose or related beta-glucans.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f9/1f9o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f9o ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the cellulase Cel48F from C. Cellulolyticum with the thiooligosaccharide inhibitor PIPS-IG3===
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==See Also==
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10985769}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10985769 is the PubMed ID number.
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[[Category: Ruminiclostridium cellulolyticum]]
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[[Category: Belaich JP]]
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{{ABSTRACT_PUBMED_10985769}}
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[[Category: Driguez H]]
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[[Category: Haser R]]
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==About this Structure==
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[[Category: Parsiegla G]]
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1F9O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9O OCA].
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[[Category: Reverbel-Leroy C]]
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[[Category: Tardif C]]
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==Reference==
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Crystal structures of the cellulase Cel48F in complex with inhibitors and substrates give insights into its processive action., Parsiegla G, Reverbel-Leroy C, Tardif C, Belaich JP, Driguez H, Haser R, Biochemistry. 2000 Sep 19;39(37):11238-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10985769 10985769]
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[[Category: Cellulase]]
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[[Category: Clostridium cellulolyticum]]
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[[Category: Single protein]]
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[[Category: Belaich, J P.]]
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[[Category: Driguez, H.]]
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[[Category: Haser, R.]]
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[[Category: Parsiegla, G.]]
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[[Category: Reverbel-Leroy, C.]]
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[[Category: Tardif, C.]]
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[[Category: Cellulase]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Thiooligosaccharide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:55:28 2008''
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Current revision

Crystal structure of the cellulase Cel48F from C. Cellulolyticum with the thiooligosaccharide inhibitor PIPS-IG3

PDB ID 1f9o

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