1fa7

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{{Seed}}
 
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[[Image:1fa7.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF CD(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI==
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The line below this paragraph, containing "STRUCTURE_1fa7", creates the "Structure Box" on the page.
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<StructureSection load='1fa7' size='340' side='right'caption='[[1fa7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fa7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FA7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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{{STRUCTURE_1fa7| PDB=1fa7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fa7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fa7 OCA], [https://pdbe.org/1fa7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fa7 RCSB], [https://www.ebi.ac.uk/pdbsum/1fa7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fa7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LGUL_ECOLI LGUL_ECOLI] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.<ref>PMID:10913283</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fa/1fa7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fa7 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF CD(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI===
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==See Also==
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*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10913283}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10913283 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_10913283}}
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==About this Structure==
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1FA7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FA7 OCA].
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==Reference==
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Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation., He MM, Clugston SL, Honek JF, Matthews BW, Biochemistry. 2000 Aug 1;39(30):8719-27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10913283 10913283]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Lactoylglutathione lyase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Clugston SL]]
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[[Category: Clugston, S L.]]
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[[Category: He MM]]
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[[Category: He, M M.]]
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[[Category: Honek JF]]
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[[Category: Honek, J F.]]
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[[Category: Matthews BW]]
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[[Category: Matthews, B W.]]
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[[Category: Beta-alpha-beta-beta-beta motif]]
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[[Category: Homodimer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:56:37 2008''
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Current revision

CRYSTAL STRUCTURE OF CD(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI

PDB ID 1fa7

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