1fdm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:28, 22 May 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1fdm.png|left|200px]]
 
-
<!--
+
==FD MAJOR COAT PROTEIN IN SDS MICELLES, NMR, 20 STRUCTURES==
-
The line below this paragraph, containing "STRUCTURE_1fdm", creates the "Structure Box" on the page.
+
<StructureSection load='1fdm' size='340' side='right'caption='[[1fdm]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1fdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_fd Enterobacteria phage fd]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FDM FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fdm OCA], [https://pdbe.org/1fdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fdm RCSB], [https://www.ebi.ac.uk/pdbsum/1fdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fdm ProSAT]</span></td></tr>
-
{{STRUCTURE_1fdm| PDB=1fdm | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CAPSD_BPFD CAPSD_BPFD] Self assembles to form a helical capsid wrapping up the viral genomic DNA. The capsid displays a filamentous structure with a length of 760-1950 nm and a width of 6-8 nm. The virion assembly and budding take place at the host inner membrane (By similarity).
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
By performing multidimensional solution NMR experiments on micelle samples it was possible to determine the structure of the membrane-bound form of fd coat protein based on short-range distance and dihedral angle constraints using distance geometry and simulated annealing calculations. Its dynamics were described by 15N relaxation measurements (T1, T2, heteronuclear nuclear Overhauser enhancement (NOE)) fitted with the Lipari-Szabo model-free formalism adapted for the transmembrane and in-plane helices of a membrane protein. The overall correlation time of the protein in micelles was found to be approximately 9 ns, and the local motion of each backbone N-H vector was described by an order parameter and an effective correlation time. The 50 residue protein has an amphipathic alpha-helix (residues 7 to 16) and a hydrophobic alpha-helix (residues 27 to 44), which were found to be approximately perpendicular on the basis of NOEs in the residues that connect the two helices. The residues connecting the helices are of particular interest in membrane proteins, and in this case the loop consists of two turns. The relaxation data show the presence of an extra motion in the amphipathic alpha-helix on the nanosecond timescale and additional flexibility of several residues in the loop connecting the two helices.
-
===FD MAJOR COAT PROTEIN IN SDS MICELLES, NMR, 20 STRUCTURES===
+
fd coat protein structure in membrane environments: structural dynamics of the loop between the hydrophobic trans-membrane helix and the amphipathic in-plane helix.,Almeida FC, Opella SJ J Mol Biol. 1997 Jul 18;270(3):481-95. PMID:9237913<ref>PMID:9237913</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 1fdm" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_9237913}}, adds the Publication Abstract to the page
+
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 9237913 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_9237913}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
1FDM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_fd Enterobacteria phage fd]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FDM OCA].
+
-
 
+
-
==Reference==
+
-
fd coat protein structure in membrane environments: structural dynamics of the loop between the hydrophobic trans-membrane helix and the amphipathic in-plane helix., Almeida FC, Opella SJ, J Mol Biol. 1997 Jul 18;270(3):481-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9237913 9237913]
+
[[Category: Enterobacteria phage fd]]
[[Category: Enterobacteria phage fd]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Almeida, F C.L.]]
+
[[Category: Almeida FCL]]
-
[[Category: Opella, S J.]]
+
[[Category: Opella SJ]]
-
[[Category: Coat protein]]
+
-
[[Category: Fd coat protein]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Micelle]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:05:40 2008''
+

Current revision

FD MAJOR COAT PROTEIN IN SDS MICELLES, NMR, 20 STRUCTURES

PDB ID 1fdm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fdm"
Personal tools