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1ffj

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{{Seed}}
 
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[[Image:1ffj.png|left|200px]]
 
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==NMR STRUCTURE OF CARDIOTOXIN IN DPC-MICELLE==
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The line below this paragraph, containing "STRUCTURE_1ffj", creates the "Structure Box" on the page.
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<StructureSection load='1ffj' size='340' side='right'caption='[[1ffj]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ffj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FFJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ffj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffj OCA], [https://pdbe.org/1ffj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ffj RCSB], [https://www.ebi.ac.uk/pdbsum/1ffj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffj ProSAT]</span></td></tr>
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{{STRUCTURE_1ffj| PDB=1ffj | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/3SA2_NAJOX 3SA2_NAJOX] This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops. Cytotoxins which have a Pro-30 (P-type) interacts with membrane stronger that those which have a 'Ser-28' (S-type). CTII interacts with membrane stronger than CTI.<ref>PMID:11357394</ref> <ref>PMID:12709064</ref> <ref>PMID:15584897</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ffj ConSurf].
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<div style="clear:both"></div>
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===NMR STRUCTURE OF CARDIOTOXIN IN DPC-MICELLE===
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==See Also==
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*[[Cardiotoxin 3D structures|Cardiotoxin 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11114253}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11114253 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_11114253}}
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==About this Structure==
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1FFJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFJ OCA].
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==Reference==
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Membrane binding motif of the P-type cardiotoxin., Dubovskii PV, Dementieva DV, Bocharov EV, Utkin YN, Arseniev AS, J Mol Biol. 2001 Jan 5;305(1):137-49. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11114253 11114253]
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[[Category: Naja oxiana]]
[[Category: Naja oxiana]]
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[[Category: Single protein]]
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[[Category: Arseniev AS]]
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[[Category: Arseniev, A S.]]
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[[Category: Bocharov EV]]
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[[Category: Bocharov, E V.]]
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[[Category: Dementieva DV]]
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[[Category: Dementieva, D V.]]
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[[Category: Dubovskii PV]]
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[[Category: Dubovskii, P V.]]
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[[Category: Utkin YN]]
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[[Category: Utkin, Y N.]]
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[[Category: All-beta sheet protein]]
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[[Category: Membrane perturbation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:10:15 2008''
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Current revision

NMR STRUCTURE OF CARDIOTOXIN IN DPC-MICELLE

PDB ID 1ffj

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