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1fgh

From Proteopedia

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{{Seed}}
 
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[[Image:1fgh.png|left|200px]]
 
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==COMPLEX WITH 4-HYDROXY-TRANS-ACONITATE==
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The line below this paragraph, containing "STRUCTURE_1fgh", creates the "Structure Box" on the page.
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<StructureSection load='1fgh' size='340' side='right'caption='[[1fgh]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fgh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FGH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATH:4-HYDROXY-ACONITATE+ION'>ATH</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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{{STRUCTURE_1fgh| PDB=1fgh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fgh OCA], [https://pdbe.org/1fgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fgh RCSB], [https://www.ebi.ac.uk/pdbsum/1fgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fgh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACON_BOVIN ACON_BOVIN] Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fg/1fgh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fgh ConSurf].
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<div style="clear:both"></div>
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===COMPLEX WITH 4-HYDROXY-TRANS-ACONITATE===
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==See Also==
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*[[Aconitase 3D structures|Aconitase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8942997}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8942997 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8942997}}
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==About this Structure==
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1FGH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FGH OCA].
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==Reference==
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The reaction of fluorocitrate with aconitase and the crystal structure of the enzyme-inhibitor complex., Lauble H, Kennedy MC, Emptage MH, Beinert H, Stout CD, Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13699-703. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8942997 8942997]
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[[Category: Aconitate hydratase]]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Beinert, H.]]
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[[Category: Beinert H]]
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[[Category: Emptage, M H.]]
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[[Category: Emptage MH]]
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[[Category: Kennedy, M C.]]
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[[Category: Kennedy MC]]
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[[Category: Lauble, H.]]
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[[Category: Lauble H]]
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[[Category: Stout, C D.]]
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[[Category: Stout CD]]
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[[Category: Complex]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:12:49 2008''
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Current revision

COMPLEX WITH 4-HYDROXY-TRANS-ACONITATE

PDB ID 1fgh

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