1frs

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[[Image:1frs.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF BACTERIOPHAGE FR CAPSIDS AT 3.5 ANGSTROMS RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_1frs", creates the "Structure Box" on the page.
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<StructureSection load='1frs' size='340' side='right'caption='[[1frs]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1frs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_fr Enterobacteria phage fr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FRS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1frs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1frs OCA], [https://pdbe.org/1frs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1frs RCSB], [https://www.ebi.ac.uk/pdbsum/1frs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1frs ProSAT]</span></td></tr>
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{{STRUCTURE_1frs| PDB=1frs | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_BPFR CAPSD_BPFR] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome. The capsid contains also 1 copy of the A2 maturation protein.[UniProtKB:P03612] Acts as a translational repressor of viral replicase synthesis late in infection. This latter function is the result of capsid protein interaction with an RNA hairpin which contains the replicase ribosome-binding site.[UniProtKB:P03612]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of recombinant capsids of the bacterial virus fr has been determined by X-ray crystallography at 3.5 A resolution. The capsids were produced by expressing the fr coat protein in Escherichia coli, the natural host of the virus, and are probably essentially identical to the protein shell of the native virus. The structure was determined using molecular replacement with the protein shell of the related MS2 virus, and refined to a crystallographic R-factor of 0.228. A comparison of the protein shells of the viruses shows that they are very similar, and indicates that they may have a similar regulation of the assembly of the quasi-symmetrical protein shell.
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===CRYSTAL STRUCTURE OF BACTERIOPHAGE FR CAPSIDS AT 3.5 ANGSTROMS RESOLUTION===
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Crystal structure of bacteriophage fr capsids at 3.5 A resolution.,Liljas L, Fridborg K, Valegard K, Bundule M, Pumpens P J Mol Biol. 1994 Dec 2;244(3):279-90. PMID:7966339<ref>PMID:7966339</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 1frs" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 7966339 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_7966339}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1FRS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_fr Enterobacteria phage fr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FRS OCA].
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==Reference==
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Crystal structure of bacteriophage fr capsids at 3.5 A resolution., Liljas L, Fridborg K, Valegard K, Bundule M, Pumpens P, J Mol Biol. 1994 Dec 2;244(3):279-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7966339 7966339]
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[[Category: Enterobacteria phage fr]]
[[Category: Enterobacteria phage fr]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bundule, M.]]
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[[Category: Bundule M]]
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[[Category: Liljas, L.]]
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[[Category: Liljas L]]
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[[Category: Valegard, K.]]
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[[Category: Valegard K]]
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[[Category: Icosahedral virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:50:56 2008''
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Current revision

CRYSTAL STRUCTURE OF BACTERIOPHAGE FR CAPSIDS AT 3.5 ANGSTROMS RESOLUTION

PDB ID 1frs

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