1fuo

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{{Seed}}
 
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[[Image:1fuo.png|left|200px]]
 
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==FUMARASE C WITH BOUND CITRATE==
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The line below this paragraph, containing "STRUCTURE_1fuo", creates the "Structure Box" on the page.
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<StructureSection load='1fuo' size='340' side='right'caption='[[1fuo]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fuo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The October 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Citric Acid Cycle'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_10 10.2210/rcsb_pdb/mom_2012_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FUO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene></td></tr>
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{{STRUCTURE_1fuo| PDB=1fuo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fuo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fuo OCA], [https://pdbe.org/1fuo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fuo RCSB], [https://www.ebi.ac.uk/pdbsum/1fuo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fuo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FUMC_ECOLI FUMC_ECOLI] Catalyzes the reversible addition of water to fumarate to give L-malate.<ref>PMID:1917897</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/1fuo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fuo ConSurf].
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<div style="clear:both"></div>
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===FUMARASE C WITH BOUND CITRATE===
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==See Also==
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*[[Fumarase|Fumarase]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_8909293}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 8909293 is the PubMed ID number.
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</StructureSection>
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[[Category: Citric Acid Cycle]]
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{{ABSTRACT_PUBMED_8909293}}
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==About this Structure==
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1FUO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUO OCA].
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==Reference==
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Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli., Weaver T, Banaszak L, Biochemistry. 1996 Nov 5;35(44):13955-65. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8909293 8909293]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Fumarate hydratase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Banaszak, L.]]
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[[Category: Banaszak L]]
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[[Category: Weaver, T.]]
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[[Category: Weaver T]]
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[[Category: Lyase]]
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[[Category: Tricarboxylic acid cycle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:58:32 2008''
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Current revision

FUMARASE C WITH BOUND CITRATE

PDB ID 1fuo

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