1fve

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{{Seed}}
 
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[[Image:1fve.png|left|200px]]
 
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==X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING==
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The line below this paragraph, containing "STRUCTURE_1fve", creates the "Structure Box" on the page.
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<StructureSection load='1fve' size='340' side='right'caption='[[1fve]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fve]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FVE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fve OCA], [https://pdbe.org/1fve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fve RCSB], [https://www.ebi.ac.uk/pdbsum/1fve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fve ProSAT]</span></td></tr>
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{{STRUCTURE_1fve| PDB=1fve | SCENE= }}
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/1fve_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fve ConSurf].
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<div style="clear:both"></div>
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===X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING===
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Sandbox 20009|Sandbox 20009]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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The line below this paragraph, {{ABSTRACT_PUBMED_8095303}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 8095303 is the PubMed ID number.
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</StructureSection>
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[[Category: Homo sapiens]]
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{{ABSTRACT_PUBMED_8095303}}
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[[Category: Large Structures]]
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[[Category: Eigenbrot C]]
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==About this Structure==
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[[Category: Kossiakoff AA]]
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1FVE is a [[Protein complex]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FVE OCA].
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[[Category: Presta L]]
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[[Category: Randal M]]
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==Reference==
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X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling., Eigenbrot C, Randal M, Presta L, Carter P, Kossiakoff AA, J Mol Biol. 1993 Feb 20;229(4):969-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8095303 8095303]
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[[Category: Protein complex]]
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[[Category: Eigenbrot, C.]]
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[[Category: Kossiakoff, A A.]]
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[[Category: Presta, L.]]
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[[Category: Randal, M.]]
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[[Category: Immunoglobulin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:00:01 2008''
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Current revision

X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING

PDB ID 1fve

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