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1ftx
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1ftx" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ftx, resolution 2.20Å" /> '''Crystal stucture of ...) |
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| - | [[Image:1ftx.gif|left|200px]]<br /><applet load="1ftx" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1ftx, resolution 2.20Å" /> | ||
| - | '''Crystal stucture of alanine racemase in complex with D-alanine phosphonate'''<br /> | ||
| - | == | + | ==Crystal structure of alanine racemase in complex with D-alanine phosphonate== |
| - | + | <StructureSection load='1ftx' size='340' side='right'caption='[[1ftx]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1ftx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FTX FirstGlance]. <br> | |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPC:(1S)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]ETHYLPHOSPHONIC+ACID'>EPC</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ftx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ftx OCA], [https://pdbe.org/1ftx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ftx RCSB], [https://www.ebi.ac.uk/pdbsum/1ftx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ftx ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/ALR_GEOSE ALR_GEOSE] Catalyzes the interconversion of L-alanine and D-alanine. Also weakly active on serine.<ref>PMID:10502689</ref> <ref>PMID:12203980</ref> | |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/1ftx_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ftx ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Alanine racemase 3D structures|Alanine racemase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Geobacillus stearothermophilus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ringe D]] | ||
| + | [[Category: Stamper GF]] | ||
Current revision
Crystal structure of alanine racemase in complex with D-alanine phosphonate
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