This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1g2y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:59, 3 April 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1g2y.png|left|200px]]
 
-
<!--
+
==HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12==
-
The line below this paragraph, containing "STRUCTURE_1g2y", creates the "Structure Box" on the page.
+
<StructureSection load='1g2y' size='340' side='right'caption='[[1g2y]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1g2y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G2Y FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_1g2y| PDB=1g2y | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g2y OCA], [https://pdbe.org/1g2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g2y RCSB], [https://www.ebi.ac.uk/pdbsum/1g2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g2y ProSAT]</span></td></tr>
-
 
+
</table>
-
===HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/HNF1A_MOUSE HNF1A_MOUSE] Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.<ref>PMID:19289501</ref> <ref>PMID:10966642</ref>
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11106484}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 11106484 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Large Structures]]
-
{{ABSTRACT_PUBMED_11106484}}
+
[[Category: Mus musculus]]
-
 
+
[[Category: Alber T]]
-
==About this Structure==
+
[[Category: Cronk JD]]
-
1G2Y is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2Y OCA].
+
[[Category: Endrizzi JA]]
-
 
+
[[Category: Holton J]]
-
==Reference==
+
[[Category: Rose RB]]
-
High-resolution structure of the HNF-1alpha dimerization domain., Rose RB, Endrizzi JA, Cronk JD, Holton J, Alber T, Biochemistry. 2000 Dec 12;39(49):15062-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11106484 11106484]
+
-
[[Category: Single protein]]
+
-
[[Category: Alber, T.]]
+
-
[[Category: Cronk, J D.]]
+
-
[[Category: Endrizzi, J A.]]
+
-
[[Category: Holton, J.]]
+
-
[[Category: Rose, R B.]]
+
-
[[Category: Dimerization domain]]
+
-
[[Category: Four-helix bundle]]
+
-
[[Category: Selenomethionine]]
+
-
[[Category: Transcription factor]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:20:13 2008''
+

Current revision

HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12

PDB ID 1g2y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1g2y"
Personal tools