1g4x

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{{Seed}}
 
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[[Image:1g4x.png|left|200px]]
 
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==ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R292L==
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The line below this paragraph, containing "STRUCTURE_1g4x", creates the "Structure Box" on the page.
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<StructureSection load='1g4x' size='340' side='right'caption='[[1g4x]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1g4x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G4X FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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{{STRUCTURE_1g4x| PDB=1g4x | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g4x OCA], [https://pdbe.org/1g4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g4x RCSB], [https://www.ebi.ac.uk/pdbsum/1g4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g4x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AAT_ECOLI AAT_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g4/1g4x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g4x ConSurf].
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<div style="clear:both"></div>
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===ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R292L===
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==See Also==
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*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11148029}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11148029 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11148029}}
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==About this Structure==
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1G4X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G4X OCA].
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==Reference==
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Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase., Mizuguchi H, Hayashi H, Okada K, Miyahara I, Hirotsu K, Kagamiyama H, Biochemistry. 2001 Jan 16;40(2):353-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11148029 11148029]
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[[Category: Aspartate transaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Mizuguchi, H.]]
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[[Category: Mizuguchi H]]
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[[Category: Active site mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:25:02 2008''
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Current revision

ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R292L

PDB ID 1g4x

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