1g8u

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{{Seed}}
 
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[[Image:1g8u.png|left|200px]]
 
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==MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGAATF5UCGCG):5-FORMYLURIDINE/ ADENOSINE BASE-PAIRS IN B-DNA==
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The line below this paragraph, containing "STRUCTURE_1g8u", creates the "Structure Box" on the page.
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<StructureSection load='1g8u' size='340' side='right'caption='[[1g8u]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1g8u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G8U FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UFR:2-DEOXY-5-FORMYLURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UFR</scene></td></tr>
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{{STRUCTURE_1g8u| PDB=1g8u | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g8u OCA], [https://pdbe.org/1g8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g8u RCSB], [https://www.ebi.ac.uk/pdbsum/1g8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g8u ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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To investigate the role of divalent cations in crystal packing, four different crystals of a Dickerson-type dodecamer with the sequence d(CGCGAATXCGCG), containing 2'-deoxy-5-formyluridine at X, were obtained under several conditions with and without divalent cations. The crystal structures are all isomorphous. The octahedrally hydrated magnesium cations found in the major groove cement the two neighbouring duplexes along the b axis. In the Mg(2+)-free crystals, a five-membered ring of water molecules occupies the same position as the magnesium site and connects the two duplexes similarly to the hydrated Mg(2+) ion. It has been concluded that water molecules can take the place of the hydrated magnesium cation in crystallization, but the magnesium cation is more effective and gives X-ray diffraction at slightly higher resolution. In all four crystals, the 5-formyluracil residues form the canonical Watson-Crick pair with adenine residues.
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===MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGAATF5UCGCG):5-FORMYLURIDINE/ ADENOSINE BASE-PAIRS IN B-DNA===
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Crystallization and preliminary X-ray analysis of a DNA dodecamer containing 2'-deoxy-5-formyluridine; what is the role of magnesium cation in crystallization of Dickerson-type DNA dodecamers?,Tsunoda M, Karino N, Ueno Y, Matsuda A, Takenaka A Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):345-8. PMID:11173500<ref>PMID:11173500</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_11173500}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1g8u" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 11173500 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_11173500}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G8U OCA].
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[[Category: Karino N]]
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[[Category: Matsuda A]]
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==Reference==
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[[Category: Takenaka A]]
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Crystallization and preliminary X-ray analysis of a DNA dodecamer containing 2'-deoxy-5-formyluridine; what is the role of magnesium cation in crystallization of Dickerson-type DNA dodecamers?, Tsunoda M, Karino N, Ueno Y, Matsuda A, Takenaka A, Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):345-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11173500 11173500]
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[[Category: Tsunoda M]]
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[[Category: Karino, N.]]
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[[Category: Ueno Y]]
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[[Category: Matsuda, A.]]
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[[Category: Takenaka, A.]]
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[[Category: Tsunoda, M.]]
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[[Category: Ueno, Y.]]
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[[Category: Deoxyribonucleic acid]]
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[[Category: Dna damage,b-dna]]
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[[Category: Double helix]]
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[[Category: Formyluridine]]
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[[Category: Modified nucleotide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:54:01 2008''
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Current revision

MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGAATF5UCGCG):5-FORMYLURIDINE/ ADENOSINE BASE-PAIRS IN B-DNA

PDB ID 1g8u

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