1gpc

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{{Seed}}
 
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[[Image:1gpc.png|left|200px]]
 
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==CORE GP32, DNA-BINDING PROTEIN==
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The line below this paragraph, containing "STRUCTURE_1gpc", creates the "Structure Box" on the page.
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<StructureSection load='1gpc' size='340' side='right'caption='[[1gpc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1gpc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GPC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1gpc| PDB=1gpc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gpc OCA], [https://pdbe.org/1gpc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gpc RCSB], [https://www.ebi.ac.uk/pdbsum/1gpc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gpc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SSB_BPT4 SSB_BPT4] Single-stranded DNA-binding protein that participates in viral DNA replication, recombination, and repair (Probable). Coats the lagging-strand ssDNA as the replication fork advances (PubMed:9079662). Stimulates the activities of viral DNA polymerase and DnaB-like SF4 replicative helicase, probably via its interaction with the helicase assembly factor (PubMed:14871889). Together with DnaB-like SF4 replicative helicase and the helicase assembly factor, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions and mediates homologous DNA strand exchange (PubMed:11459967). Promotes also the formation of joint molecules (PubMed:9079662). mRNA specific autogenous translational repressor (PubMed:15507125).[HAMAP-Rule:MF_04152]<ref>PMID:11459967</ref> <ref>PMID:14871889</ref> <ref>PMID:15507125</ref> <ref>PMID:9079662</ref> <ref>PMID:9079662</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gp/1gpc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gpc ConSurf].
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<div style="clear:both"></div>
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===CORE GP32, DNA-BINDING PROTEIN===
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==See Also==
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*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 7630406 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia virus T4]]
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{{ABSTRACT_PUBMED_7630406}}
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[[Category: Large Structures]]
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[[Category: Friedman AM]]
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==About this Structure==
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[[Category: Konigsberg WH]]
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1GPC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GPC OCA].
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[[Category: Parsons MR]]
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[[Category: Shamoo Y]]
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==Reference==
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[[Category: Steitz TA]]
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Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA., Shamoo Y, Friedman AM, Parsons MR, Konigsberg WH, Steitz TA, Nature. 1995 Jul 27;376(6538):362-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7630406 7630406]
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[[Category: Enterobacteria phage t4]]
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[[Category: Single protein]]
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[[Category: Friedman, A M.]]
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[[Category: Konigsberg, W H.]]
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[[Category: Parsons, M R.]]
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[[Category: Shamoo, Y.]]
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[[Category: Steitz, T A.]]
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[[Category: Single-stranded dna-binding]]
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[[Category: Ssb]]
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[[Category: Zinc binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 05:38:35 2008''
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Current revision

CORE GP32, DNA-BINDING PROTEIN

PDB ID 1gpc

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