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1gup

From Proteopedia

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{{Seed}}
 
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[[Image:1gup.png|left|200px]]
 
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<!--
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==STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GALACTOSE==
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The line below this paragraph, containing "STRUCTURE_1gup", creates the "Structure Box" on the page.
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<StructureSection load='1gup' size='340' side='right'caption='[[1gup]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1gup]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1gup| PDB=1gup | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gup OCA], [https://pdbe.org/1gup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gup RCSB], [https://www.ebi.ac.uk/pdbsum/1gup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gup ProSAT]</span></td></tr>
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</table>
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===STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GALACTOSE===
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== Function ==
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[https://www.uniprot.org/uniprot/GAL7_ECOLI GAL7_ECOLI]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_9063869}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9063869 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/1gup_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9063869}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1GUP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUP OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gup ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural analysis of the H166G site-directed mutant of galactose-1-phosphate uridylyltransferase complexed with either UDP-glucose or UDP-galactose: detailed description of the nucleotide sugar binding site., Thoden JB, Ruzicka FJ, Frey PA, Rayment I, Holden HM, Biochemistry. 1997 Feb 11;36(6):1212-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9063869 9063869]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: UTP--hexose-1-phosphate uridylyltransferase]]
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[[Category: Holden H]]
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[[Category: Holden, H.]]
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[[Category: Rayment I]]
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[[Category: Rayment, I.]]
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[[Category: Thoden JB]]
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[[Category: Thoden, J B.]]
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[[Category: Galactose metabolism]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:06:46 2008''
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Current revision

STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GALACTOSE

PDB ID 1gup

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