1gxg
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1gxg.png|left|200px]] | ||
| - | < | + | ==Non-cognate protein-protein interactions: the NMR structure of the colicin E8 inhibitor protein Im8 and its interaction with the DNase domain of colicin E9== |
| - | + | <StructureSection load='1gxg' size='340' side='right'caption='[[1gxg]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1gxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1imz 1imz]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GXG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxg OCA], [https://pdbe.org/1gxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gxg RCSB], [https://www.ebi.ac.uk/pdbsum/1gxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gxg ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IMM8_ECOLX IMM8_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE8 encoding colicin E8, against colicin E8, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxg_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gxg ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Boetzel | + | [[Category: Boetzel R]] |
| - | [[Category: Czisch | + | [[Category: Czisch M]] |
| - | + | [[Category: James R]] | |
| - | [[Category: James | + | [[Category: Kleanthous C]] |
| - | [[Category: Kleanthous | + | [[Category: Le Duff CS]] |
| - | [[Category: | + | [[Category: Moore GR]] |
| - | [[Category: | + | [[Category: Videler H]] |
| - | [[Category: | + | |
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Current revision
Non-cognate protein-protein interactions: the NMR structure of the colicin E8 inhibitor protein Im8 and its interaction with the DNase domain of colicin E9
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