1hcr

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{{Seed}}
 
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[[Image:1hcr.png|left|200px]]
 
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==HIN RECOMBINASE BOUND TO DNA: THE ORIGIN OF SPECIFICITY IN MAJOR AND MINOR GROOVE INTERACTIONS==
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The line below this paragraph, containing "STRUCTURE_1hcr", creates the "Structure Box" on the page.
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<StructureSection load='1hcr' size='340' side='right'caption='[[1hcr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hcr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HCR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hcr OCA], [https://pdbe.org/1hcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hcr RCSB], [https://www.ebi.ac.uk/pdbsum/1hcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hcr ProSAT]</span></td></tr>
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{{STRUCTURE_1hcr| PDB=1hcr | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/1hcr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hcr ConSurf].
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<div style="clear:both"></div>
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===HIN RECOMBINASE BOUND TO DNA: THE ORIGIN OF SPECIFICITY IN MAJOR AND MINOR GROOVE INTERACTIONS===
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8278807}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8278807 is the PubMed ID number.
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Dickerson RE]]
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{{ABSTRACT_PUBMED_8278807}}
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[[Category: Feng J-A]]
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[[Category: Johnson RC]]
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==About this Structure==
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1HCR is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HCR OCA].
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==Reference==
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Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions., Feng JA, Johnson RC, Dickerson RE, Science. 1994 Jan 21;263(5145):348-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8278807 8278807]
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[[Category: Single protein]]
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[[Category: Dickerson, R E.]]
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[[Category: Feng, J A.]]
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[[Category: Johnson, R C.]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 07:59:59 2008''
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Current revision

HIN RECOMBINASE BOUND TO DNA: THE ORIGIN OF SPECIFICITY IN MAJOR AND MINOR GROOVE INTERACTIONS

PDB ID 1hcr

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