This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1hpg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:34, 27 March 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1hpg.png|left|200px]]
 
-
<!--
+
==A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding==
-
The line below this paragraph, containing "STRUCTURE_1hpg", creates the "Structure Box" on the page.
+
<StructureSection load='1hpg' size='340' side='right'caption='[[1hpg]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1hpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HPG FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOC:TERT-BUTYL+HYDROGEN+CARBONATE'>BOC</scene></td></tr>
-
{{STRUCTURE_1hpg| PDB=1hpg | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hpg OCA], [https://pdbe.org/1hpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hpg RCSB], [https://www.ebi.ac.uk/pdbsum/1hpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hpg ProSAT]</span></td></tr>
-
 
+
</table>
-
===A GLUTAMIC ACID SPECIFIC SERINE PROTEASE UTILIZES A NOVEL HISTIDINE TRIAD IN SUBSTRATE BINDING===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/GLUP_STRGR GLUP_STRGR] Preferentially cleaves peptide bonds on the carboxyl-terminal side of glutamate.
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_8105890}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 8105890 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hp/1hpg_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_8105890}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1HPG is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HPG OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hpg ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding., Nienaber VL, Breddam K, Birktoft JJ, Biochemistry. 1993 Nov 2;32(43):11469-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8105890 8105890]
+
</StructureSection>
-
[[Category: Glutamyl endopeptidase II]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Streptomyces griseus]]
-
[[Category: Birktoft, J J.]]
+
[[Category: Birktoft JJ]]
-
[[Category: Nienaber, V L.]]
+
[[Category: Nienaber VL]]
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:30:08 2008''
+

Current revision

A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding

PDB ID 1hpg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hpg"
Personal tools