1hsq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:35, 27 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1hsq.png|left|200px]]
 
-
<!--
+
==SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA==
-
The line below this paragraph, containing "STRUCTURE_1hsq", creates the "Structure Box" on the page.
+
<StructureSection load='1hsq' size='340' side='right'caption='[[1hsq]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1hsq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HSQ FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsq OCA], [https://pdbe.org/1hsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hsq RCSB], [https://www.ebi.ac.uk/pdbsum/1hsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hsq ProSAT]</span></td></tr>
-
{{STRUCTURE_1hsq| PDB=1hsq | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PLCG1_HUMAN PLCG1_HUMAN] Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.<ref>PMID:17229814</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hs/1hsq_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hsq ConSurf].
 +
<div style="clear:both"></div>
-
===SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA===
+
==See Also==
-
 
+
*[[Phospholipase C|Phospholipase C]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_7681365}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 7681365 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_7681365}}
+
-
 
+
-
==About this Structure==
+
-
1HSQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HSQ OCA].
+
-
 
+
-
==Reference==
+
-
Solution structure of the SH3 domain of phospholipase C-gamma., Kohda D, Hatanaka H, Odaka M, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F, Cell. 1993 Mar 26;72(6):953-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7681365 7681365]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Phosphoinositide phospholipase C]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Hatanaka H]]
-
[[Category: Hatanaka, H.]]
+
[[Category: Inagaki F]]
-
[[Category: Inagaki, F.]]
+
[[Category: Kohda D]]
-
[[Category: Kohda, D.]]
+
[[Category: Odaka M]]
-
[[Category: Odaka, M.]]
+
-
[[Category: Phosphoric diester hydrolase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:37:53 2008''
+

Current revision

SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA

PDB ID 1hsq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hsq"
Personal tools