1hxt

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{{Seed}}
 
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[[Image:1hxt.png|left|200px]]
 
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==OMPF PORIN MUTANT NQAAA==
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The line below this paragraph, containing "STRUCTURE_1hxt", creates the "Structure Box" on the page.
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<StructureSection load='1hxt' size='340' side='right'caption='[[1hxt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hxt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HXT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
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{{STRUCTURE_1hxt| PDB=1hxt | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxt OCA], [https://pdbe.org/1hxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hxt RCSB], [https://www.ebi.ac.uk/pdbsum/1hxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/1hxt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hxt ConSurf].
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<div style="clear:both"></div>
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===OMPF PORIN MUTANT NQAAA===
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==See Also==
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*[[Porin 3D structures|Porin 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11371193}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11371193 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_11371193}}
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==About this Structure==
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1HXT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXT OCA].
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==Reference==
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Role of charged residues at the OmpF porin channel constriction probed by mutagenesis and simulation., Phale PS, Philippsen A, Widmer C, Phale VP, Rosenbusch JP, Schirmer T, Biochemistry. 2001 May 29;40(21):6319-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11371193 11371193]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Phale, P S.]]
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[[Category: Phale PS]]
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[[Category: Phale, V P.]]
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[[Category: Phale VP]]
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[[Category: Philippsen, A.]]
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[[Category: Philippsen A]]
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[[Category: Rosenbusch, J P.]]
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[[Category: Rosenbusch JP]]
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[[Category: Schirmer, T.]]
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[[Category: Schirmer T]]
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[[Category: Widmer, C.]]
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[[Category: Widmer C]]
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[[Category: Beta barrel]]
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[[Category: Membrane protein]]
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[[Category: Porin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:05:53 2008''
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Current revision

OMPF PORIN MUTANT NQAAA

PDB ID 1hxt

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