1i0h

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{{Seed}}
 
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[[Image:1i0h.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE MUTANT Y174F AT 1.35 ANGSTROMS RESOLUTION.==
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The line below this paragraph, containing "STRUCTURE_1i0h", creates the "Structure Box" on the page.
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<StructureSection load='1i0h' size='340' side='right'caption='[[1i0h]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i0h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I0H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_1i0h| PDB=1i0h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0h OCA], [https://pdbe.org/1i0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i0h RCSB], [https://www.ebi.ac.uk/pdbsum/1i0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i0/1i0h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i0h ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE MUTANT Y174F AT 1.35 ANGSTROMS RESOLUTION.===
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==See Also==
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11294629}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11294629 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11294629}}
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==About this Structure==
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1I0H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0H OCA].
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==Reference==
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Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity., Edwards RA, Whittaker MM, Whittaker JW, Baker EN, Jameson GB, Biochemistry. 2001 Apr 17;40(15):4622-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11294629 11294629]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Superoxide dismutase]]
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[[Category: Baker EN]]
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[[Category: Baker, E N.]]
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[[Category: Edwards RA]]
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[[Category: Edwards, R A.]]
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[[Category: Jameson GB]]
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[[Category: Jameson, G B.]]
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[[Category: Whittaker JW]]
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[[Category: Whittaker, J W.]]
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[[Category: Whittaker MM]]
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[[Category: Whittaker, M M.]]
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[[Category: Hydrogen bond]]
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[[Category: Manganese superoxide dismutase]]
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[[Category: Reactivity]]
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[[Category: Y174f mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:13:31 2008''
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Current revision

CRYSTAL STRUCTURE OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE MUTANT Y174F AT 1.35 ANGSTROMS RESOLUTION.

PDB ID 1i0h

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