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1i6b

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{{Seed}}
 
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[[Image:1i6b.png|left|200px]]
 
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==STRUCTURE OF EQUINE APOLACTOFERRIN AT 3.2 A RESOLUTION USING CRYSTALS GROWN AT 303K==
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The line below this paragraph, containing "STRUCTURE_1i6b", creates the "Structure Box" on the page.
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<StructureSection load='1i6b' size='340' side='right'caption='[[1i6b]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I6B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6b OCA], [https://pdbe.org/1i6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i6b RCSB], [https://www.ebi.ac.uk/pdbsum/1i6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i6b ProSAT]</span></td></tr>
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{{STRUCTURE_1i6b| PDB=1i6b | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRFL_HORSE TRFL_HORSE] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/1i6b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i6b ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF EQUINE APOLACTOFERRIN AT 3.2 A RESOLUTION USING CRYSTALS GROWN AT 303K===
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==See Also==
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*[[Lactoferrin|Lactoferrin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11807246}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11807246 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11807246}}
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==About this Structure==
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1I6B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6B OCA].
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==Reference==
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Crystal structure of equine apolactoferrin at 303 K providing further evidence of closed conformations of N and C lobes., Kumar P, Khan JA, Yadav S, Singh TP, Acta Crystallogr D Biol Crystallogr. 2002 Feb;58(Pt 2):225-32. Epub 2002, Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11807246 11807246]
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[[Category: Equus caballus]]
[[Category: Equus caballus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kumar, P.]]
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[[Category: Kumar P]]
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[[Category: Singh, T P.]]
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[[Category: Singh TP]]
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[[Category: Yadav, S.]]
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[[Category: Yadav S]]
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[[Category: Apo]]
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[[Category: Crystal]]
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[[Category: Equine]]
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[[Category: Lactoferrin]]
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[[Category: Structure]]
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[[Category: Transferrin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:28:43 2008''
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Current revision

STRUCTURE OF EQUINE APOLACTOFERRIN AT 3.2 A RESOLUTION USING CRYSTALS GROWN AT 303K

PDB ID 1i6b

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