1i8k

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{{Seed}}
 
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[[Image:1i8k.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE==
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The line below this paragraph, containing "STRUCTURE_1i8k", creates the "Structure Box" on the page.
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<StructureSection load='1i8k' size='340' side='right'caption='[[1i8k]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i8k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I8K FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i8k OCA], [https://pdbe.org/1i8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i8k RCSB], [https://www.ebi.ac.uk/pdbsum/1i8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i8k ProSAT]</span></td></tr>
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{{STRUCTURE_1i8k| PDB=1i8k | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KV3A8_MOUSE KV3A8_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/1i8k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i8k ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE===
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_11352579}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 11352579 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_11352579}}
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==About this Structure==
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1I8K is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8K OCA].
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==Reference==
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Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII., Landry RC, Klimowicz AC, Lavictoire SJ, Borisova S, Kottachchi DT, Lorimer IA, Evans SV, J Mol Biol. 2001 May 18;308(5):883-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11352579 11352579]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Borisova S]]
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[[Category: Borisova, S.]]
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[[Category: Evans SV]]
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[[Category: Evans, S V.]]
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[[Category: Klimowicz AC]]
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[[Category: Klimowicz, A C.]]
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[[Category: Kottachchi DT]]
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[[Category: Kottachchi, D T.]]
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[[Category: Landry RC]]
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[[Category: Landry, R C.]]
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[[Category: Lavictoire SJ]]
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[[Category: Lavictoire, S J.]]
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[[Category: Lorimer IA]]
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[[Category: Lorimer, I A.]]
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[[Category: Antibody-peptide complex]]
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[[Category: Immunoglobulin fold]]
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[[Category: Peptide antigen]]
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[[Category: Type ii' beta turn.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:35:05 2008''
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Current revision

CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE

PDB ID 1i8k

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