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1i9g

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{{Seed}}
 
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[[Image:1i9g.png|left|200px]]
 
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<!--
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==CRYSTAL STRUCTURE OF AN ADOMET DEPENDENT METHYLTRANSFERASE==
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The line below this paragraph, containing "STRUCTURE_1i9g", creates the "Structure Box" on the page.
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<StructureSection load='1i9g' size='340' side='right'caption='[[1i9g]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1i9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I9G FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_1i9g| PDB=1i9g | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i9g OCA], [https://pdbe.org/1i9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i9g RCSB], [https://www.ebi.ac.uk/pdbsum/1i9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i9g ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF AN ADOMET DEPENDENT METHYLTRANSFERASE===
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== Function ==
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[https://www.uniprot.org/uniprot/TRMI_MYCTU TRMI_MYCTU] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.<ref>PMID:14960715</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11554794}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11554794 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i9/1i9g_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11554794}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1I9G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I9G OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i9g ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv., Gupta A, Kumar PH, Dineshkumar TK, Varshney U, Subramanya HS, J Mol Biol. 2001 Sep 14;312(2):381-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11554794 11554794]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
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[[Category: Dineshkumar TK]]
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[[Category: Dineshkumar, T K.]]
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[[Category: Gupta A]]
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[[Category: Gupta, A.]]
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[[Category: Kumar PH]]
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[[Category: Kumar, P H.]]
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[[Category: Subramanya HS]]
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[[Category: Subramanya, H S.]]
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[[Category: Varshney U]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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[[Category: Varshney, U.]]
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[[Category: Adomet]]
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[[Category: Crystal]]
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[[Category: Mtase]]
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[[Category: Mycobacterium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Tb structural genomics consortium]]
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[[Category: Tbsgc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:37:30 2008''
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Current revision

CRYSTAL STRUCTURE OF AN ADOMET DEPENDENT METHYLTRANSFERASE

PDB ID 1i9g

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