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1juh

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{{Seed}}
 
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[[Image:1juh.png|left|200px]]
 
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==Crystal Structure of Quercetin 2,3-dioxygenase==
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The line below this paragraph, containing "STRUCTURE_1juh", creates the "Structure Box" on the page.
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<StructureSection load='1juh' size='340' side='right'caption='[[1juh]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1juh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_japonicus Aspergillus japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JUH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1juh| PDB=1juh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1juh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1juh OCA], [https://pdbe.org/1juh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1juh RCSB], [https://www.ebi.ac.uk/pdbsum/1juh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1juh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/QDOI_ASPJA QDOI_ASPJA] Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavonol quercetin yielding the depside 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. This involves the remarkable dioxygenolytic cleavage of two carbon-carbon bonds.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/1juh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1juh ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Quercetin 2,3-dioxygenase===
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==See Also==
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*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11839311}}, adds the Publication Abstract to the page
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[[Category: Aspergillus japonicus]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11839311 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Dijkstra BW]]
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{{ABSTRACT_PUBMED_11839311}}
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[[Category: Fusetti F]]
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[[Category: Schroeter KH]]
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==About this Structure==
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[[Category: Steiner RA]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUH OCA].
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==Reference==
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Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus., Fusetti F, Schroter KH, Steiner RA, van Noort PI, Pijning T, Rozeboom HJ, Kalk KH, Egmond MR, Dijkstra BW, Structure. 2002 Feb;10(2):259-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11839311 11839311]
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[[Category: Quercetin 2,3-dioxygenase]]
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[[Category: Dijkstra, B W.]]
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[[Category: Fusetti, F.]]
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[[Category: Schroeter, K H.]]
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[[Category: Steiner, R A.]]
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[[Category: Beta sandwich]]
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[[Category: Copper]]
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[[Category: Cupin]]
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[[Category: Dioxygenase]]
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[[Category: Glycoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:54:12 2008''
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Current revision

Crystal Structure of Quercetin 2,3-dioxygenase

PDB ID 1juh

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