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1juo

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{{Seed}}
 
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[[Image:1juo.png|left|200px]]
 
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==Crystal Structure of Calcium-free Human Sorcin: A Member of the Penta-EF-Hand Protein Family==
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The line below this paragraph, containing "STRUCTURE_1juo", creates the "Structure Box" on the page.
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<StructureSection load='1juo' size='340' side='right'caption='[[1juo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1juo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JUO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1juo OCA], [https://pdbe.org/1juo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1juo RCSB], [https://www.ebi.ac.uk/pdbsum/1juo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1juo ProSAT]</span></td></tr>
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{{STRUCTURE_1juo| PDB=1juo | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Calcium-free Human Sorcin: A Member of the Penta-EF-Hand Protein Family===
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[https://www.uniprot.org/uniprot/SORCN_HUMAN SORCN_HUMAN] Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.<ref>PMID:17699613</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11714909}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11714909 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/1juo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11714909}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1juo ConSurf].
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1JUO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUO OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of calcium-free human sorcin: a member of the penta-EF-hand protein family., Xie X, Dwyer MD, Swenson L, Parker MH, Botfield MC, Protein Sci. 2001 Dec;10(12):2419-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11714909 11714909]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Xie, X.]]
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[[Category: Xie X]]
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[[Category: Calcium-binding protein]]
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[[Category: Pef]]
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[[Category: Penta-ef-hand]]
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[[Category: X-ray]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:55:29 2008''
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Current revision

Crystal Structure of Calcium-free Human Sorcin: A Member of the Penta-EF-Hand Protein Family

PDB ID 1juo

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