1k1q

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{{Seed}}
 
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[[Image:1k1q.png|left|200px]]
 
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==Crystal Structure of a DinB Family Error Prone DNA Polymerase from Sulfolobus solfataricus==
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The line below this paragraph, containing "STRUCTURE_1k1q", creates the "Structure Box" on the page.
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<StructureSection load='1k1q' size='340' side='right'caption='[[1k1q]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1k1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K1Q FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k1q OCA], [https://pdbe.org/1k1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k1q RCSB], [https://www.ebi.ac.uk/pdbsum/1k1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k1q ProSAT]</span></td></tr>
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{{STRUCTURE_1k1q| PDB=1k1q | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of a DinB Family Error Prone DNA Polymerase from Sulfolobus solfataricus===
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[https://www.uniprot.org/uniprot/DPO4_SACSO DPO4_SACSO] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11685247 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/1k1q_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11685247}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k1q ConSurf].
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1K1Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K1Q OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus., Silvian LF, Toth EA, Pham P, Goodman MF, Ellenberger T, Nat Struct Biol. 2001 Nov;8(11):984-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11685247 11685247]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Sulfolobus solfataricus]]
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[[Category: Ellenberger T]]
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[[Category: Ellenberger, T.]]
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[[Category: Goodman MF]]
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[[Category: Goodman, M F.]]
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[[Category: Pham P]]
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[[Category: Pham, P.]]
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[[Category: Silvian LF]]
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[[Category: Silvian, L F.]]
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[[Category: Toth EA]]
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[[Category: Toth, E A.]]
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[[Category: Dna polymerase]]
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[[Category: Error-prone polymerase]]
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[[Category: Lesion-bypass polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 21:18:55 2008''
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Current revision

Crystal Structure of a DinB Family Error Prone DNA Polymerase from Sulfolobus solfataricus

PDB ID 1k1q

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