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1k2h

From Proteopedia

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{{Seed}}
 
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[[Image:1k2h.png|left|200px]]
 
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==Three-dimensional Solution Structure of apo-S100A1.==
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The line below this paragraph, containing "STRUCTURE_1k2h", creates the "Structure Box" on the page.
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<StructureSection load='1k2h' size='340' side='right'caption='[[1k2h]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1k2h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K2H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k2h OCA], [https://pdbe.org/1k2h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k2h RCSB], [https://www.ebi.ac.uk/pdbsum/1k2h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k2h ProSAT]</span></td></tr>
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{{STRUCTURE_1k2h| PDB=1k2h | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S10A1_RAT S10A1_RAT] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/1k2h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k2h ConSurf].
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<div style="clear:both"></div>
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===Three-dimensional Solution Structure of apo-S100A1.===
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==See Also==
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*[[S100 proteins 3D structures|S100 proteins 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11790100}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11790100 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_11790100}}
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==About this Structure==
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1K2H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2H OCA].
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==Reference==
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Three-dimensional solution structure of the calcium-signaling protein apo-S100A1 as determined by NMR., Rustandi RR, Baldisseri DM, Inman KG, Nizner P, Hamilton SM, Landar A, Landar A, Zimmer DB, Weber DJ, Biochemistry. 2002 Jan 22;41(3):788-96. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11790100 11790100]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
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[[Category: Baldisseri DM]]
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[[Category: Baldisseri, D M.]]
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[[Category: Hamilton SM]]
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[[Category: Hamilton, S M.]]
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[[Category: Inman KG]]
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[[Category: Inman, K G.]]
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[[Category: Landar A]]
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[[Category: Landar, A.]]
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[[Category: Nizner P]]
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[[Category: Nizner, P.]]
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[[Category: Rustandi RR]]
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[[Category: Rustandi, R R.]]
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[[Category: Weber DJ]]
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[[Category: Weber, D J.]]
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[[Category: Zimmer DB]]
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[[Category: Zimmer, D B.]]
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[[Category: Non-covalent homodimer]]
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[[Category: X-type four-helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 21:32:47 2008''
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Current revision

Three-dimensional Solution Structure of apo-S100A1.

PDB ID 1k2h

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